Tech and Computer

Tech and Computer news




Last update06:42:42 PM GMT

Back Computer Science Computational Biology

Computational Biology

Computational modeling can help plan vaccine introduction, study finds

  • PDF
TechAndComputer (Sep. 29, 2011) — Proper planning before the introduction of new vaccines into a developing country's active immunization program could prevent storage problems and transportation bottlenecks that decrease the availability of existing vaccines by as much as two-thirds, according to a University of Pittsburgh study.

Computational models can assess the evolving needs of the vaccine supply chain -- or the series of steps required to get a vaccine from the manufacturer to the target population. The modeling can forecast the impact of new vaccine introduction and identify potential disruptions, concluded the study, which will appear in the November issue of the American Journal of Public Health.

"Our study...

New targets for the control of HIV predicted using a novel computational analysis

  • PDF
TechAndComputer (Sep. 22, 2011) — A new computational approach has predicted numerous human proteins that the human immunodeficiency virus (HIV) requires to replicate itself. These discoveries "constitute a powerful resource for experimentalists who desire to discover new targets for human proteins that can control the spread of HIV," according to the authors of this study that appears in the Sept. 22, 2011 issue of PLoS Computational Biology, a...

TechAndComputer (Sep. 22, 2011) — A new...

Computational method predicts new uses for existing medicines; Match-making program uses gene expression patterns

  • PDF
TechAndComputer (Aug. 17, 2011) — For the first time ever, scientists are using computers and genomic information to predict new uses for existing medicines.

A National Institutes of Health-funded computational study analyzed genomic and drug data to predict new uses for medicines that are already on the market. A team led by Atul J. Butte, M.D., Ph.D., of Stanford University, Palo Alto, Calif., reports its results in two articles in the Aug. 17...

TechAndComputer (Aug. 17, 2011) — For...

Novel analysis method organizes genomic cancer data

  • PDF
TechAndComputer (June 30, 2011) — The technology that allows scientists to profile the entire genome of individual tumors offers new hope for discovering ways to select the best treatment for each patient's particular type of cancer. However, these profiles produce huge amounts of data, and the volume alone creates unique analytical problems.

In a study published online this week in the journal BMC Medical Genomics, researchers from Huntsman Cancer Institute (HCI) at the...

Next-generation gene sequencing brings personal genomics closer, IDs mutation in new syndrome

  • PDF
TechAndComputer (June 24, 2011) — Harnessing the new generation of rapid, highly accurate gene-sequencing techniques, a research team has identified the disease-causing mutation in a newly characterized rare genetic disease, by analyzing DNA from just a few individuals. The power and speed of the innovative bioinformatics tool marks a step toward personalized genomics -- discovering causative mutations in individual patients.

"Our research is...

TechAndComputer (June 24, 2011) —...