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Computational software provides rapid identification of disease-causing gene variations

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TechAndComputer (June 24, 2011) — Scientists from the University of Utah and Omicia, Inc., a privately held company developing tools to interpret personal genome sequences, have announced the publication in Genome Research of a new software tool called VAAST, the Variant Annotation, Analysis and Selection Tool -- a probabilistic disease-causing mutation finder for individual human genomes.

The dramatic decline in DNA sequencing costs is making...

TechAndComputer (June 24, 2011) — Scientists from the University of Utah and Omicia, Inc., a privately held company developing tools to interpret personal genome sequences, have announced the publication in Genome Research of a new software tool called VAAST, the Variant Annotation, Analysis...

New supercomputer will chase novel genes

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TechAndComputer (June 16, 2011) — With 4000 times as much memory as an ordinary PC, the new supercomputer enables DTU researchers to rapidly identify new genes and proteins that can be used in future sustainable biotechnology industrial processes. The computer, which is an Altix UV 1000 model supplied by SGI, has been named Anakyklosis which is the Greek word for recycling. The name reflects its importance to a biologically sustainable future.

"Sy...

TechAndComputer (June 16, 2011) — With...

'Networking' turns up flu viruses with close ties to pandemic of 2009

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TechAndComputer (June 13, 2011) — Scientists using new mathematical and computational techniques have identified six influenza A viruses that have particularly close genetic relationships to the H1N1 "swine" flu virus that swept through the United States beginning in the spring of 2009. That virus eventually killed almost 18,000 people worldwide.

Biological studies focused on these strains of influenza virus could shed light on how the 2009...

TechAndComputer (June 13, 2011) — Scientists...

New computer algorithm improves method for finding genetic mistakes that fuel cancer

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TechAndComputer (June 13, 2011) — A dramatically better computer tool for finding the genetic missteps that fuel cancer has been developed by St. Jude Children's Research Hospital -- Washington University Pediatric Cancer Genome Project investigators. Researchers are using the new algorithm to help identify the chromosomal rearrangements and DNA insertions or deletions unique to cancer.

The new computational method is known as CREST, short for...

TechAndComputer (June 13, 2011) — A...

Chasing EHEC via computer: Scientists in Germany provide free access to enteric pathogen's genetic regulation data

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TechAndComputer (June 12, 2011) — Just a few genes make enterohaemorrhagic E. coli (EHEC) extremely dangerous to humans. If it were not for these genes, EHEC would hardly differ from harmless enteric bacteria. Bioinformatics scientists from the Saarbrücken Cluster of Excellence want to exploit this similarity to find starting points for effective drugs against the EHEC pathogen. In a very short time, the scientists have constructed EhecRegNet, a...

TechAndComputer (June 12, 2011) — Just a...